Executive Order 14407: Realigning United States Core Childhood Vaccine Recommendations With Best Practices From Peer, Developed Countries
President: Donald J. Trump
Directed HHS and CDC to compare the US core childhood immunization schedule with peer-country practices and consider revisions through established recommendation processes.
Status: In effect.
Is Executive Order 14407 still in effect? Yes. Active; comparative review of childhood schedule directed.

What does Executive Order 14407 do?
The text directs HHS and CDC to conduct peer-country and evidence review, and ACIP to consider recommendations through public process.
Reading the operative provisions of Executive Order 14407
EO 14407 directs HHS and CDC to compare the U.S. core childhood immunization schedule with practices in peer countries and consider revisions through established scientific recommendation processes. It asks the Advisory Committee on Immunization Practices to review evidence and recommendations. The Federal Register text initiates comparison and review; it does not itself change the schedule, vaccine labels or school-entry requirements.
CDC recommendations are developed through evidence review, public meetings and formal agency adoption. ACIP considers disease burden, vaccine safety and effectiveness, implementation and other evidence. A recommendation, CDC adoption, FDA product label and state school requirement are separate decisions. The order cannot bypass those processes or turn another country’s schedule into a U.S. rule automatically.
EO 14420 later delivered a follow-up action on childhood vaccine recommendations, and the Federal Register record should be read with EO 14407 to see how the policy developed. Families should use current CDC guidance and consult health professionals about individual care. To assess the order’s effect, look for ACIP materials, CDC adoption notices and any later rules or state actions rather than infer a schedule change from the original directive.
Comparing schedules requires attention to differences in disease prevalence, health systems, vaccine products, dosage intervals and access. A peer-country comparison can identify questions for review, but it cannot establish that one country’s schedule is automatically safer or more effective in the United States. CDC and ACIP must evaluate evidence relevant to U.S. conditions. EO 14420 is a later follow-up action; the recommendation process and adoption records show what, if anything, changed.
Before and after
Before the order
US recommendations were developed through CDC and the Advisory Committee on Immunization Practices using disease, safety, effectiveness and implementation evidence.
After the order
The order initiated comparative review; recommendations, product labels and school requirements remain distinct legal and scientific decisions.
Federal Register, agency, amendment, revocation and court sources were searched through September 15, 2026. No revocation or material order-specific final court ruling was located; comparative review completed; later recommendation work follows eo 14420 and established processes.
Who had to do what
| Agency / office | Action | Timing / position |
|---|---|---|
| HHS and CDC | Conduct peer-country and evidence review | Ongoing |
| ACIP | Consider recommendations through public process | Meeting-specific |
| Agencies | Assess program and coverage implications | After recommendations |
What happened next
EO 14407 signed.
Legal and source detail
How it works legally
The Public Health Service Act, Federal Advisory Committee Act, FDCA, Vaccines for Children statute, state school law and judicial review remain. The order does not itself change a product license.
Sources by type
If a source is unavailable, first check the cited publisher or another official repository. The cited publisher remains the authority.
Primary and official sources
Orders, laws, court records and official implementation material.
How we checked this
Last checked against the sources above on September 15, 2026. How we research →